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Symbol
Name
ID
Slitrk2
SLIT and NTRK-like family, member 2
MGI:2679449
Phenotype annotations related to nervous system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Spasticity
Ventriculomegaly
Hippocampal atrophy
Thin corpus callosum
Corpus callosum atrophy
Reduced cerebral white matter volume
Cerebral palsy
Phonic tics
Absent speech
Delayed speech and language development
Anxiety
Autistic behavior
Aggressive behavior
Compulsive behaviors
Hyperactivity
Intellectual disability
Dystonia
Unsteady gait
Global developmental delay
Seizure
Disease(s) Associated with SLITRK2
non-syndromic X-linked intellectual developmental disorder 111

Mouse Phenotypes
nervous system phenotype
abnormal serotonergic neuron morphology
abnormal synapse morphology
abnormal postsynaptic density morphology
abnormal excitatory synapse morphology
abnormal excitatory postsynaptic potential
abnormal miniature excitatory postsynaptic currents
Availability Mouse Genotype
Slitrk2tm1.1Jaru/Slitrk2tm1.1Jaru *
Slitrk2tm1.1Jwum/Y
Tg(Nes-cre)1Atp/0  (conditional)
Slitrk2tm1.1Jwum/Y  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory